LA JOLLA—Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. A tumor’s microenvironment—the nearby tissues, immune cells, blood vessels and extracellular matrix—has long been known to play a role in the tumor’s growth.

A team of scientists led by prof. Adrian Liston (VIB–KU Leuven) and prof. Isabelle Meyts (UZ Leuven – KU Leuven) were able to characterize a new genetic immunodeficiency resulting from a mutation in a gene named STAT2. This mutation causes patients to be extremely vulnerable to normally mild childhood illnesses such as rotavirus and enterovirus. Prof. Liston’s comprehensive analysis of the genetic defect allows clinicians to provide children with the proper therapies before illnesses prove fatal. The findings of the research have been published in the Journal of Allergy and Clinical Immunology.

Lugano, Switzerland – Biosimilars create opportunities for sustainable cancer care, says the European Society for Medical Oncology (ESMO) in a position paper published in ESMO Open. The document outlines approval standards for biosimilars, how to safely introduce them into the clinic, and the potential benefits for patients and healthcare systems.

A study led by scientists at the Translational Genomics Research Institute (TGen) has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer.

Aurintricarboxylic Acid (ATA) is a chemical compound that in laboratory tests was shown to block the chemical cascade that otherwise allows glioblastoma cells to invade normal brain tissue and resist both chemo and radiation therapy, according to a TGen-led report published today in the scientific journal Oncotarget.

 

China has canceled plans for more than 100 new coal-fired power plants, including several that were already under construction, according to news reports. The power stations, with an estimated price tag of $62 billion, would have had an electricity-generating capacity of more than 100 gigawatts, spread across several provinces.

In August 2015, a dust storm blanketed large areas of seven Middle East nations in a haze of dust and sand thick enough to obscure them from satellite view. The storm led to several deaths, thousands of cases of respiratory ailments and injuries, and canceled airline flights and closed ports. 

At the time, the storm's unusual severity was attributed to the ongoing civil war in Syria by media outlets in the Middle East, Europe and the United States. Reports blamed the conflict for changes in land use and cover — and for activities like increased military traffic over unpaved surfaces and farmers reducing irrigation or abandoning agricultural land — that created extreme amounts of dust to fuel the storm.

The mineral erionite is considered to be highly carcinogenic and is on the World Health Organisation's list of substances that cause cancer. A few years ago, an entire village in Turkey actually had to be moved, because the substance was very common in the surrounding area and every second inhabitant died of a particular type of cancer caused by breathing in erionite particles. Up to now it has been thought that iron as a constituent element of the mineral erionite is the reason for the carcinogenic effect. However, mineralogists of Friedrich Schiller University Jena (Germany), together with colleagues from the University of Modena (Italy), have discovered that this metal does not even appear in the crystal structure of erionite.

Authorities in Beijing are taking new actions to resolve the city’s ongoing and harmful air pollution problem with the creation of an anti-smog police force — but will it help?

Beijing’s acting mayor Cai Qi reportedly announced the initiative on Saturday, January 7. The dedicated branch of regulation enforcement will patrol the streets looking specifically for violations that could harm air quality, including open air barbecues, unlicensed burning of materials and improperly maintained roads.

If water rates continue rising at projected amounts, the number of U.S. households unable to afford water could triple in five years, to nearly 36 percent, finds new research by a Michigan State University scholar.

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system’s ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.