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Scientists have shown that a process known as oxidative stress is at work during encounters between certain nanoparticles and immune cells, selectively modifying proteins on macrophages, a type of immune cell. The findings, by researchers at the Department of Energy's Pacific Northwest National Laboratory, were published in the journal ACS Nano.

While oxidative stress is a common way for cell damage to occur, the findings were a surprise in some ways.

"Oxidative stress is occurring selectively even at low levels of exposure to nanoparticles," said Brian Thrall, a nanotoxicology expert at PNNL and a corresponding author of the study. "We've demonstrated an approach that is sensitive enough to detect effects of nanoparticles on macrophages long before those cells die. This gives us the opportunity to understand the most sensitive cellular targets of oxidative stress and the pathways involved more completely than before.

"This is important information for understanding how nanoparticles can alter cell function and for beginning to identify functions that allow cells to adapt versus those that are potentially involved in adverse effects," Thrall added.

The Greenland Ice Sheet is the second largest ice sheet in the world and it's melting rapidly, likely driving almost a third of global sea level rise.

A new study shows clouds are playing a larger role in that process than scientists previously believed.

"Over the next 80 years, we could be dealing with another foot of sea level rise around the world," says Tristan L'Ecuyer, professor in the Department of Atmospheric and Oceanic Sciences at the University of Wisconsin-Madison and co-author of the study. "Parts of Miami and New York City are less than two feet above sea level; another foot of sea level rise and suddenly you have water in the city."

Durante los últimos seis años, los investigadores de la Universidad Politécnica de Valencia (UPV) han estado estudiando el rendimiento de doce variedades de pino carrasco (especie arbórea de la familia de las pináceas, género Pinus, NT) nativas de diferentes regiones de España en campañas de reforestación a través de tres áreas forestales nacionales. Las diferentes variedades o genotipos tienen diferentes niveles de resistencia al frío y la sequía, que influyen en lo bien que subsisten en una región geográfica determinada y los investigadores querían saber qué variedades funcionaban mejor y dónde.

Senators Kevin de León and Fran Pavley announced a package of new legislation that builds on Gov. Brown’s state of emergency declaration to ensure protections for Californians impacted by the natural gas leak in Porter Ranch. 

The new legislation will require: 

• a moratorium on new injections into the Aliso Canyon  storage facility until experts determine it is safe to resume and a study to see whether it makes sense to continue using the facility. (SB 875)
• that response costs – such as greenhouse gas mitigation, relocation, and emergency response costs – will be funded by the Gas Company shareholders, not the ratepayers who are suffering from this disaster. (SB 876)
• stronger laws regulating gas storage facilities, including increased inspections and health and safety measures. (SB 877)
• setting state climate pollution reduction targets and holding polluters accountable for meeting those targets. (SB 878)

An international team of scientists has shed new light on the earthquake that devastated Nepal in April 2015, killing more than 8,000 people.

In a study published in the journal Nature Geoscience, the scientists show that a kink in the regional fault line below Nepal explains why the highest mountains in the Himalayas are seen to grow between earthquakes.