Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

These findings are based on two studies featured in the latest issue of Cancer Prevention Research.

The first was a preclinical study, led by Karen Liby, an associate professor in the Department of Pharmacology and Toxicology. Results showed that the drug, I-BET-762, is showing signs of significantly delaying the development of existing breast and lung cancers by zeroing in on how a cancerous gene, called c-Myc, acts.

Scientists have developed a new technique to examine the effects of chemicals on digestive systems of fish and support research into gut related conditions. It also has potential to reduce the number of animal experiments, in line with the principles of the 3Rs (Reduce, Refine and Replace).

Obesity is a big problem, and UNLV biologist Allen Gibbs has enlisted millions of six-legged volunteers to help him figure out the genetic basis of a plight that affects an increasing number of Americans.

Optical Mammography, or OM, which uses harmless red or infrared light, has been developed for use in conjunction with X-rays for diagnosis or monitoring in cases demanding repeated imaging where high amounts of ionizing radiation should be avoided. At the OSA Biophotonics Congress: Biomedical Optics meeting, held 3-6 April in Hollywood, Florida, USA, researchers from Milan, Italy, will report an advance in instrument development that increases the sensitivity of OM by as much as 1000-fold.

A team of researchers has developed a wearable, non-invasive system to monitor electrical activity in the stomach over 24 hours—essentially an electrocardiogram but for the gastro-intestinal (GI) tract.

Pain can be valuable. Without it, we might let our hand linger on a hot stove, for example. But longer-lasting pain, such as the inflammatory pain that can arise after injury, can be debilitating and costly, preventing us from completing important tasks. In natural settings, the lethargy triggered by such pain could even hinder survival. 

Engineers at wastewater recycling plants can rest easy knowing that their methods for minimizing the formation of a potent carcinogen are targeting the right chemical compound.

Researchers at Chalmers University of Technology have shown that between 87 and 98 percent of ships comply with the tougher regulations for sulphur emissions that were introduced in northern Europe in 2015. The lowest levels of compliance were observed in the western part of the English Channel and in the middle of the Baltic Sea.

Queen’s University researcher Xiaolong Yang and his research team have developed a light emission-based biosensor that uses firefly luciferase (the enzyme that allows fireflies to light up) to monitor cancer cell activity and help find new ways to fight the spread of cancer.

A UT Southwestern study in mice provides new clues about how a class of anti-rejection drugs used after organ transplants may also slow the progression of early-stage Alzheimer’s disease.