The report estimates that there will be 1,735,350 new cancer cases and 609,640 cancer deaths in the United States in 2018*. The cancer death rate dropped 26% from its peak of 215.1 per 100,000 population in 1991 to 158.6 per 100,000 in 2015. A significant proportion of the drop is due to steady reductions in smoking and advances in early detection and treatment. The overall decline is driven by decreasing death rates for the four major cancer sites: Lung (declined 45% from 1990 to 2015 among men and 19% from 2002 to 2015 among women); female breast (down 39% from 1989 to 2015), prostate (down 52% from 1993 to 2015), and colorectal (down 52% from 1970 to 2015).
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