As Canadians brace for “vitamin D winter” – months when the sun’s angle is too low to produce the vitamin in the skin – a McGill University study explains why vitamin D deficiency early in life is associated with a higher risk of autoimmune diseases.
As Canadians brace for “vitamin D winter” – months when the sun’s angle is too low to produce the vitamin in the skin – a McGill University study explains why vitamin D deficiency early in life is associated with a higher risk of autoimmune diseases.
During childhood, the thymus helps train immune cells to distinguish between the body’s own tissues and harmful invaders. A vitamin D deficiency at that stage of life causes the thymus to age more quickly, the researchers discovered.
“An aging thymus leads to a ‘leaky’ immune system,” said lead author John White, a Professor in and Chair of McGill’s Department of Physiology. “This means the thymus becomes less effective at filtering out immune cells that could mistakenly attack healthy tissues, increasing the risk of autoimmune diseases like Type 1 diabetes.”
Read More: McGill University
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