Gene editing has been a much sought after and controversial technology.
Gene editing has been a much sought after and controversial technology. Last month, part of the World Health Organization called for an international registry to track all research into editing the human genome.
Purdue University researchers, including one who was inspired by the cancer death of a close friend, have developed a new technology that could change how gene editing is approached in the future. The research team presents the work on April 4 at the National Meeting of the American Chemical Society in Orlando.
One of the most widely used methods for gene editing is CRISPR-Cas9 technology. The method requires a certain sequence or motif for function that restricts modifications.
“CRISPR can be programmed to cut DNA at specific regions to make precise edits in an organism that can increase sustainable manufacturing, treat disease and even create better crops,” said Kevin Solomon, an assistant professor of agricultural and biological engineering, who leads the Purdue research team. “However, it requires a certain sequence for function that restricts modifications to certain regions.”
Read more at Purdue University
Photo: Purdue University researchers have developed a new technology that could change how gene editing is approached. NgAgo is programmed with guide DNA (red) to cut DNA (purple) at specific regions, enabling precise genetic modifications. CREDIT: Purdue University
