Air Pollution Linked to Heart Remodelling

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Researchers have found that people exposed to air pollution levels well within UK guidelines have changes in the structure of the heart, similar to those seen in the early stages of heart failure.

Researchers have found that people exposed to air pollution levels well within UK guidelines have changes in the structure of the heart, similar to those seen in the early stages of heart failure.

A team of scientists, led from Queen Mary University of London by Professor Steffen Petersen, studied data from around 4,000 participants in the UK Biobank study. Volunteers provided a range of personal information, including their lifestyles, health record and details on where they have lived. Participants also had blood tests and health scans.

Even though most participants lived outside major UK cities, there was a clear association between those who lived near loud, busy roads, and were exposed to nitrogen dioxide (NO2) or PM2.5 - small particles of air pollution – and the development of larger right and left ventricles in the heart. The ventricles are important pumping chambers in the heart and, although these participants were healthy and had no symptoms, similar heart remodelling is seen in the early stages of heart failure.

Higher exposures to the pollutants were linked to more significant changes in the structure of the heart. For every 1 extra µg per cubic metre of PM2.5 and for every 10 extra µg per cubic of NO2, the heart enlarges by approximately 1% .

Read more at British Heart Foundation

Image: Research from the UK has found that people exposed to even low levels of air pollution have heart remodelling, similar to that seen in the early stages of heart failure. (Credit: British Heart Foundation)