Cinnamon turns up the heat on fat cells

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New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice—cinnamon—might be enlisted in the fight against obesity.

Scientists had previously observed that cinnamaldehyde, an essential oil that gives cinnamon its flavor, appeared to protect mice against obesity and hyperglycemia. But the mechanisms underlying the effect were not well understood.

New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice—cinnamon—might be enlisted in the fight against obesity.

Scientists had previously observed that cinnamaldehyde, an essential oil that gives cinnamon its flavor, appeared to protect mice against obesity and hyperglycemia. But the mechanisms underlying the effect were not well understood.

Researchers in the lab of Jun Wu, research assistant professor at the LSI, wanted to better understand cinnamaldehyde's action and determine whether it might be protective in humans, too.

"Scientists were finding that this compound affected metabolism," said Wu, who also is an assistant professor of molecular and integrative physiology at the U-M Medical School. "So we wanted to figure out how—what pathway might be involved, what it looked like in mice and what it looked like in human cells."

 

Continue reading at University of Michigan.

Image via University of Michigan.