The common fruit fly, the tiny insect drawn to your beer or wine, has evolved to have an impressive tolerance for alcohol.
More than two decades ago, in one of the first papers using gene sequences to find signatures of natural selection, scientists hypothesized that a molecular change in an enzyme gave the Drosophila melanogaster fruit fly species its superior ability to metabolize alcohol. Scientists concluded that the change they found in the Alcohol dehydrogenase (ADH) protein could be the adaptation that allowed D. melanogaster to colonize ethanol-rich habitats in rotting fruit better than its nearly identical relative, Drosophila simulans.
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