• Blocking a key enzyme may reverse memory loss

    In the brains of Alzheimer’s patients, many of the genes required to form new memories are shut down by a genetic blockade, contributing to the cognitive decline seen in those patients.

    MIT researchers have now shown that they can reverse that memory loss in mice by interfering with the enzyme that forms the blockade. The enzyme, known as HDAC2, turns genes off by condensing them so tightly that they can’t be expressed.

    For several years, scientists and pharmaceutical companies have been trying to develop drugs that block this enzyme, but most of these drugs also block other members of the HDAC family, which can lead to toxic side effects. The MIT team has now found a way to precisely target HDAC2, by blocking its interaction with a binding partner called Sp3.

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  • Laser mapping project shows effects of physical changes in Antarctica's Dry Valleys

    Researchers funded by the National Science Foundation (NSF) have publicly released high-resolution maps of Antarctica's McMurdo Dry Valleys, a globally unique polar desert.

    The high-resolution maps cover 3,564 square kilometers of the McMurdo Dry Valleys and allow researchers to compare present-day conditions with lower-resolution LIDAR surveys conducted almost 13 years ago.

    Scientists from Portland State University led the new research project, which mapped the area using more sophisticated LIDAR, a remote-sensing method that uses laser beam pulses to measure the distance from the detector to the Earth's surface.

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  • Vertical Axis Wind Turbines Can Offer Cheaper Electricity for Urban and Suburban Areas

    According to a prediction made by the U.S. Department of Energy, wind energy could provide 20 percent of electricity in the U.S. by the year 2030. This has motivated researchers from the University of Utah’s Department of Mechanical Engineering to investigate the performance capabilities and financial benefits of vertical axis wind turbines (VAWTs) in urban and suburban areas. 

    A VAWT is a wind turbine design where the generator is vertically oriented in the tower, rather than sitting horizontally on top. While there are many VAWT designs, the one used in this study is called the straight-blade Darrieus type or H-rotor turbine.

    According to the researchers, small VAWTs possess the ability to effectively operate in the presence of high turbulent flow, which makes them ideal energy harvesting devices in urban and suburban environments. In an article in this week’s Journal of Renewable and Sustainable Energy, from AIP Publishing, the authors present results indicating that an optimally designed VAWT system can financially compete with fossil-fuel based power plants in urban and suburban areas, and even spearhead the development of a net-zero energy building or city. 

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  • Simultaneous Design and Nanomanufacturing Speeds Up Fabrication

    Design and nanomanufacturing have collided inside of a Northwestern University laboratory.

    An interdisciplinary team of researchers has used mathematics and machine learning to design an optimal material for light management in solar cells, then fabricated the nanostructured surfaces simultaneously with a new nanomanufacturing technique.

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  • Standard Model of the Universe Withstands Most Precise Test by Dark Energy Survey

    Astrophysicists have a fairly accurate understanding of how the universe ages: That’s the conclusion of new results from the Dark Energy Survey (DES), a large international science collaboration, including researchers from the Department of Energy’s SLAC National Accelerator Laboratory, that put models of cosmic structure formation and evolution to the most precise test yet.

    The survey’s researchers analyzed light from 26 million galaxies to study how structures in the universe have changed over the past 7 billion years – half the age of the universe. The data were taken with the DECam, a 570-megapixel camera attached to the 4-meter Victor M. Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile.

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  • Primordial Black Holes May Have Helped to Forge Heavy Elements

    Astronomers like to say we are the byproducts of stars, stellar furnaces that long ago fused hydrogen and helium into the elements needed for life through the process of stellar nucleosynthesis.

    As the late Carl Sagan once put it: “The nitrogen in our DNA, the calcium in our teeth, the iron in our blood, the carbon in our apple pies were made in the interiors of collapsing stars. We are made of star stuff.”

    But what about the heavier elements in the periodic chart, elements such as gold, platinum and uranium?

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  • Blood from MERS Virus Survivors May Help Target Treatments

    Since causing major outbreaks in Saudi Arabia in 2014, and in Korea a year later, the virus that causes Middle East Respiratory Syndrome is laying low. But by no means has it disappeared: A recent cluster of 34 cases cropped up in July in Riyadh City, Saudi Arabia’s capital. The dromedary camels who harbored the virus for more than 20 years aren’t going anywhere, and neither is MERS.

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  • Isotope fingerprints in feathers reveal songbirds' secret breeding grounds

    Using isotope fingerprints in feathers, researchers have pinpointed the northern breeding grounds of a small, colourful songbird.

    Myrtle warblers breed across much of Canada and the eastern United States, but winter in two distinct groups—one along the Atlantic and Gulf coasts, another along the US Pacific Coast. They are also one of the few breeds of eastern warbler that have been able to extend their range into the far northwest of the continent.

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  • Tropical Depression 11E ''Born'' With Wind Shear on Satellite Imagery

    The eleventh tropical depression of the Eastern Pacific Ocean hurricane season came together on August 4 even though it was being affected by vertical wind shear.

    NOAA's GOES-West satellite captured a visible image of Tropical Depression 11E on August 4, 2017 at 10:45 a.m. EDT (1445 UTC) in the Eastern Pacific Ocean. The image showed that the bulk of clouds appeared on the western side of the storm, which indicates wind shear was likely affecting the storm. 

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  • NASA's Voyager Spacecraft Still Reaching for the Stars

    Humanity's farthest and longest-lived spacecraft, Voyager 1 and 2, achieve 40 years of operation and exploration this August and September. Despite their vast distance, they continue to communicate with NASA daily, still probing the final frontier. Their story has not only impacted generations of current and future scientists and engineers, but also Earth's culture, including film, art, and music. Each spacecraft carries a Golden Record of Earth sounds, pictures, and messages. Since the spacecraft could last billions of years, these circular time capsules could one day be the only traces of human civilization.

    "None of us knew, when we launched 40 years ago, that anything would still be working, and continuing on this pioneering journey," said Ed Stone, Voyager project scientist at Caltech in Pasadena, California. "The most exciting thing they find in the next five years is likely to be something that we didn't know was out there to be discovered."

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