articles

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. In a new paper published this week in Cancer Cell, Mayo Clinic researchers provide genetic evidence that Ect2 drives lung adenocarcinoma tumor formation.

LA JOLLA—Normally when we think of viruses, from the common cold to HIV, we want to boost people’s immunity to fight them. But for scientists who develop therapeutic viruses (to, for example, target cancer cells or correct gene deficiencies) a more important question is: How do we keep people’s natural immune responses at bay? In these cases, an overenthusiastic immune response actually undermines the therapy.

Aerial tree mortality surveys show patterns of tree death during extreme drought.

Why do some trees die in a drought and others don’t? And how can we predict where trees are most likely to die in future droughts?

LA JOLLA—Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. A tumor’s microenvironment—the nearby tissues, immune cells, blood vessels and extracellular matrix—has long been known to play a role in the tumor’s growth.

When epidemiological data are scarce, social media and Internet reports can be reliable tools for forecasting infectious disease outbreaks, according to a study led by an expert in the School of Public Health at Georgia State University.

“Our study offers proof of concept that publicly available online reports released in real-time by ministries of health, local surveillance systems, the World Health Organization and authoritative media outlets are useful to identify key information on exposure and transmission patterns during epidemic emergencies,” the researchers said. “Our Internet-based findings on exposure patterns are in good agreement with those derived from traditional epidemiological surveillance data, which can be available after considerable delays.”