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The tenth SpaceX cargo resupply launch to the International Space Station, targeted for launch Feb. 18, will deliver investigations that study human health, Earth science and weather patterns. Here are some highlights of the research headed to the orbiting laboratory:

Crystal growth investigation could improve drug delivery, manufacturing

Monoclonal antibodies are important for fighting off a wide range of human diseases, including cancers. These antibodies work with the natural immune system to bind to certain molecules to detect, purify and block their growth. The Microgravity Growth of Crystalline Monoclonal Antibodies for Pharmaceutical Applications (CASIS PCG 5) investigation will crystallize a human monoclonal antibody, developed by Merck Research Labs, that is currently undergoing clinical trials for the treatment of immunological disease.

While international efforts are underway to protect iconic monarch butterflies from disappearing, the latest population count has found their numbers have dropped by nearly one-third since last year.

According to the Xerces Society for Invertebrate Conservation, in the 1990s, an estimated one billion monarchs embarked on an epic annual migration. Their journey takes them from sites in Canada and the U.S. to wintering grounds in California and Mexico, where they find shelter and warmth among oyamel fir trees in the winter.

In order to restore tropical rainforests, it is not enough to simply set up protected areas and leave them to their own devices. In particular, tree species with large fruit and seeds distributed by birds will have to be actively planted. This is one of the conclusions of a large-scale study by scientists from ETH Zurich in the Western Ghats, the mountain range running along the western coast of India. Today, the rainforest that exists there is highly fragmented. In the late 20th century in particular, large areas fell victim to intensive logging and commercial agriculture such as coffee and tea plantations.

California sardine stocks famously crashed in John Steinbeck’s “Cannery Row.” New research, building on the pioneering work of Soutar and Isaacs in the late 1960’s and others, shows in greater detail that such forage fish stocks have undergone boom-bust cycles for centuries, with at least three species off the U.S. West Coast repeatedly experiencing steep population increases followed by declines long before commercial fishing began.

Natural population fluctuations in Pacific sardine, northern anchovy and Pacific hake off California have been so common that the species were in collapsed condition 29 to 40 percent of the time over the 500-year period from A.D. 1000 to 1500, according to the study published today in Geophysical Research Letters. Using a long time series of fish scales deposited in low-oxygen offshore sedimentary environments off southern California, the authors from NOAA Fisheries and the University of Michigan described such collapses as “an intrinsic property of some forage fish populations that should be expected, just as droughts are expected in an arid climate.” 

Savannahs form one of the largest habitats in the world, covering around one-fifth of the Earth's land area. They are mainly to be found in sub-Saharan Africa. Savannahs are home not only to unique wildlife, including the 'Big Five' - the African elephant, rhinoceros, Cape buffalo, leopard and lion - but also to thousands of endemic plant species such as the baobab, or monkey bread tree.