Patients with a rare bone cancer of the skull and spine – chordoma – could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust. In the largest genomics study of chordoma to date, published today (12 October) in Nature Communications, scientists show that a group of chordoma patients have mutations in genes that are the target of existing drugs, known as PI3K inhibitors.

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The Colorado River tumbles through varied landscapes, draining watersheds from seven western states. This 1,450-mile-long system is a critical water supply for agriculture, industry and municipalities from Denver to Tijuana.

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The dramatic rise in production of electric vehicles, coupled with expected growth in the use of grid-connected battery systems for storing electricity from renewable sources, raises a crucial question: Are there enough raw materials to enable significantly increased production of lithium-ion batteries, which are the dominant type of rechargeable batteries on the market?

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A team of scientists, led by British Antarctic Survey (BAS), is planning an urgent mission to investigate a mysterious marine ecosystem that’s been hidden beneath an Antarctic ice shelf for up to 120,000 years.  The researchers want to discover how this marine ecosystem will respond to environmental change in a climate-sensitive region.

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