Changing the natural electrical signaling that exists in cells outside the nervous system can improve resistance to life-threatening bacterial infections, according to new research from Tufts University biologists.  The researchers found that administering drugs, including those already used in humans for other purposes, to make the cell interior more negatively charged strengthens tadpoles’ innate immune response to E. coli infection and injury. This reveals a novel aspect of the immune system – regulation by non-neural bioelectricity – and suggests a new approach for clinical applications in human medicine. The study is published online May 26, 2017, in npj Regenerative Medicine, a Nature Research journal.

“All cells, not just nerve cells, naturally generate and receive electrical signals. Being able to regulate such non-neural bioelectricity with the many ion channel and neurotransmitter drugs that are already human-approved gives us an amazing new toolkit to augment the immune system’s ability to resist infections,” said the paper’s corresponding author Michael Levin, Ph.D., Vannevar Bush professor of biology and director of the Allen Discovery Center at Tufts and the Tufts Center for Regenerative and Developmental Biology in the School of Arts and Sciences. Levin is also an associate faculty member of the Wyss Institute of Biologically Inspired Engineering at Harvard University.

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Just as Cinderella turned from a poor teenager into a magnificent princess with the aid of a little magic, scientists at the U.S. Department of Energy’s Argonne National Laboratory have transformed a common metal into a useful catalyst for a wide class of reactions, a role formerly reserved for expensive precious metals.

In a new study, Argonne chemist Max Delferro boosted and analyzed the unprecedented catalytic activity of an element called vanadium for hydrogenation – a reaction that is used for making everything from vegetable oils to petrochemical products to vitamins. 

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Diesel pollution is linked with heart damage, according to research presented today at EuroCMR 2017 (1).

“There is strong evidence that particulate matter (PM) emitted mainly from diesel road vehicles is associated with increased risk of heart attack, heart failure, and death,” said lead author Dr Nay Aung, a cardiologist and Wellcome Trust research fellow, William Harvey Research Institute, Queen Mary University of London, UK. “This appears to be driven by an inflammatory response – inhalation of fine particulate matter (PM2.5) causes localised inflammation of the lungs followed by a more systemic inflammation affecting the whole body.”

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What to do proteins and Kevlar have in common? Both feature long chain molecules that are strung together by amide bonds. These strong chemical bonds are also common to many other naturally occurring molecules as well as man-made pharmaceuticals and plastics. Although amide bonds can give great strength to plastics, when it comes to their recycling at a later point, the difficultly of breaking these bonds usually prevents recovery of useful products. Catalysts are widely used in chemistry to help speed up reactions, but breaking the kinds of amide bonds in plastics, such as nylon, and other materials requires harsh conditions and large amounts of energy.

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NOAA will begin using its newest weather prediction tool -- the dynamic core, Finite-Volume on a Cubed-Sphere (FV3), to provide high quality guidance to NOAA’s National Hurricane Center through the 2017 hurricane season.

Developed by Shian-Jiann Lin and his team at NOAA’s Geophysical Fluid Dynamics Laboratory (GFDL), the FV3 will be used to power experimental hurricane forecast models that run parallel to the operational forecast models this season. This is the start of a major transition of the FV3 to NOAA operational weather forecasting, expected to be completed in 2019.

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On Wednesday May 24, 2017 severe weather affected a large area of the eastern United States. That's when the Global Precipitation Measurement mission or GPM core satellite passed over the area and found extremely heavy rainfall and towering clouds in the system.

Tornadoes were reported in Florida, Georgia, South Carolina, North Carolina and Ohio on that day. The National Weather Service noted that rainfall in Tallahassee, Florida set a record at 1.52 inches on May 24.

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