Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV. One mechanism by which they work could occur because gold ions force the zinc ions out of zinc fingers—looped, nucleic acid binding protein domains. American researchers have characterized such “gold fingers” using ion mobility mass spectrometry. As reported in the journal Angewandte Chemie, they identified the exact gold binding sites.

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At the same time the pH of the surface waters in these oceans decreased, making them more acidic. Both of these findings imply changes in ocean circulation and primary productivity as a result of natural climate changes of the time. The findings were recently published in Nature Communications.

Oceans changed function

Today the cold Arctic and Nordic Seas are especially efficient areas for uptake of CO2 from the atmosphere. The oceans have been capable of mitigating some of the increase in greenhouse gas release resulting from human activities such as combustion of fossil fuels, by absorbing about 40% of the emitted CO2

“Our research shows that areas in Norwegian Sea had changed their function on  several occasions through the past 135 000 years: Instead of absorbing CO2 from the air, they released more of the greenhouse gas into it.” says first author of the study Mohamed Ezat from Centre of Arctic Gas Hydrate, Environment and Climate (CAGE), Department of Geosciences at UiT The Arctic University of Norway.

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