Sense of Smell, Pollution and Neurological Disease Connection Explored

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A consensus is building that air pollution can cause neurological diseases such as Alzheimer's disease and Parkinson's disease, but how fine, sooty particles cause problems in the brain is still an unanswered question.

A consensus is building that air pollution can cause neurological diseases such as Alzheimer's disease and Parkinson's disease, but how fine, sooty particles cause problems in the brain is still an unanswered question. Now a team of Penn State researchers, using mice, have found a possible way, but more research is still needed.

The researchers looked at how cerebrospinal fluid, the liquid that flows around the brain and spinal cord, flows out through the nose, and what happens when the flow of fluid is stopped.

"There has been a lot of interest in understanding cerebrospinal fluid movement in the last 5 years," said Patrick Drew, Huck Distinguished Associate Professor of Engineering Science and Mechanics, Neurosurgery and Biomedical Engineering. "More and more it is realized that it does not just cushion the brain, but may also transfer stuff out of the brain and spinal column area."

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