• Hypothermia After Stroke Reduces Dynamin Levels and Neuronal Cell Death

    A new study has shown that following brain ischemia caused by cerebral blockage in mice both immediate and delayed reduction in body temperature helped limit cell death and levels of a protein called dynamin. These results, which suggest that dynamin may have a role in—and be a potential drug target for—stroke-related neuronal cell death, are reported in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal website until September 16, 2017.

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  • New Report Outlines Research Agenda to Better Understand the Relationship Among Microbiomes, Indoor Environments, and Human Health

    Even with a growing body of research on microorganisms and humans in indoor environments, many of their interconnections remain unknown, says a new report by the National Academies of Sciences, Engineering, and Medicine. The report proposes a research agenda to gain a more comprehensive understanding of the formation, dynamics, and functions of indoor microbiomes that can guide improvements to current and future buildings as well as enhance human health and well-being.

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  • New Tool Aims to Make Surgery Safer by Helping Doctors See Nerves

    During operations, it can be difficult for surgeons to avoid severing crucial nerves because they look so much like other tissue. A new noninvasive approach that uses polarized light to make nerves stand out from other tissue could help surgeons avoid accidentally injuring nerves or assist them in identifying nerves in need of repair.

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  • Antifreeze to improve aeroplanes, ice cream and organ transplants

    The design of airplane wings and storing organs for transplant could both become safer and more effective, thanks to a synthetic antifreeze which prevents the growth of ice crystals, developed by researchers at the University of Warwick.

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  • A new method of 3D printing living tissues

    The approach could revolutionise regenerative medicine, enabling the production of complex tissues and cartilage that would potentially support, repair or augment diseased and damaged areas of the body.

    Printing high-resolution living tissues is hard to do, as the cells often move within printed structures and can collapse on themselves. But, led by Professor Hagan Bayley, Professor of Chemical Biology in Oxford’s Department of Chemistry, the team devised a way to produce tissues in self-contained cells that support the structures to keep their shape.

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  • Mercury is altering gene expression

    The mercury found at very low concentrations in water is concentrated along the entire food chain, from algae via zooplankton to small fish and on to the largest fish — the ones we eat. Mercury causes severe and irreversible neurological disorders in people who have consumed highly contaminated fish. Whereas we know about the element’s extreme toxicity, what happens further down the food chain, all the way down to those microalgae that are the first level and the gateway for mercury? By employing molecular biology tools, a team of researchers from the University of Geneva (UNIGE), Switzerland, has addressed this question for the first time. The scientists measured the way mercury affects the gene expression of algae, even when its concentration in water is very low, comparable to European environmental protection standards. Find out more about the UNIGE research in Scientific Reports.

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  • Air pollution linked to cardiovascular disease; air purifiers may lessen impact

    Exposure to high levels of air pollution increased stress hormone levels and negative metabolic changes in otherwise healthy, young adults in a recent study conducted in China. Air purifiers appeared to lessen the negative effects, according to new research published in the American Heart Association’s journal Circulation.

    Researchers focused on fine particulate matter (PM2.5) – a component of air pollution emitted from vehicles, factories, power plants, fires and smoking – because many studies have suggested this type of major air pollutant might lead to cardiovascular and metabolic health consequences, according to Haidong Kan, M.D., Ph.D., study author and professor of environmental health sciences at Fudan University in Shanghai, China.

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  • Lights, camera, CRISPR: Biologists use gene editing to store movies in DNA

    Internet users have a variety of format options in which to store their movies, and biologists have now joined the party. Researchers have used the microbial immune system CRISPR–Cas to encode a movie into the genome of the bacterium Escherichia coli.

    The technical achievement, reported on 12 July in Nature, is a step towards creating cellular recording systems that are capable of encoding a series of events, says Seth Shipman, a synthetic biologist at Harvard Medical School in Boston, Massachusetts. While studying brain development, Shipman became frustrated by the lack of a technique to capture how cells in the brain take on distinct identities. This inspired him to explore the possibility of making cellular recorders.

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  • Feeling bad about feeling bad can make you feel worse

    Pressure to feel upbeat can make you feel downbeat, while embracing your darker moods can actually make you feel better in the long run, according to new UC Berkeley research.

    “We found that people who habitually accept their negative emotions experience fewer negative emotions, which adds up to better psychological health,” said study senior author Iris Mauss, an associate professor of psychology at UC Berkeley.

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  • Pennsylvania Hospital Neurosurgeon Performs the First Endoscopic Minimally Invasive Spinal Surgery in Pennsylvania

    Spine disc related low back and leg pain is a major challenge and is the second most common reason that patients visit the doctor in the United States—outnumbered only be respiratory infections—and is the leading cause of disability worldwide. Compression of the spinal nerves is one of the most common diagnoses and is frequently reversible with surgery.

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