EPA Toxicity Information On Line

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The U.S. Environmental Protection Agency (EPA) is making it easier to find chemical information online. EPA is releasing a database, called ToxRefDB, which allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of federal required testing results. In this day and age this is a handy regulatory and technical tool and simplifies at leash some of the required toxicity investigation research.

The U.S. Environmental Protection Agency (EPA) is making it easier to find chemical information online. EPA is releasing a database, called ToxRefDB, which allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of federal required testing results. In this day and age this is a handy regulatory and technical tool and simplifies at leash some of the required toxicity investigation research.

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ToxRefDB provides detailed chemical toxicity data in an accessible format. It is a part of ACToR (Aggregated Computational Toxicology Resource), an online data warehouse that collects data from about 500 public sources on tens of thousands of environmentally relevant chemicals, including several hundred in ToxRefDB. Those interested in chemical toxicity can query a specific chemical and find all available public hazard, exposure, and risk assessment data, as well as previously unpublished studies related to cancer, reproductive, and developmental toxicity.

The database:

1. Contains pesticide registration toxicity data that used to be stored as hard-copy and scanned documents.

2. Includes chronic, cancer, sub-chronic, developmental, and reproductive studies on hundreds of chemicals (many are pesticide active ingredients).

3. Provides data that is accessible and computable.

4. Provides reference toxicity data for Agency research and retrospective analyses.

Only certain hazard information is going to be found and the database, though useful, does not represent all information needed for a complete risk assessment for pesticides or other chemicals. Please note that not every possible chemical of concern is listed and only those that relate mostly to pesticides type risks.

As an example one can find on this database:

Alternate names

Physical/chemical properties

Development effects

Reproductive and carcinogenic effects

State, federal and Canadian references

This EPA database does make it easier to research some chemicals of concern.

In Europe there is the REACH program whose aim is to improve the protection of human health and the environment through the better and earlier identification of the intrinsic properties of chemical substances. This will require a lot of new toxicity testing and sharing such information (as in this search engine) will help to reduce costs and improve the effectiveness of the REACH program.

Note the second web address below directly connects to the new toxics database.

For further information: http://www.eurekalert.org/pub_releases/2010-04/uepa-eoa042910.php or http://actor.epa.gov/toxrefdb/faces/Home.jsp